研究证实：乳腺癌患者的伴侣易患抑郁症

导读：最新研究发现，女性乳腺癌患者的男性伴侣患抑郁症等精神类疾病的比例高出常人4成。

最新研究发现，女性乳腺癌患者的男性伴侣患抑郁症等精神类疾病的比例高出常人4成。

丹麦癌症学会最新发布的研究报告指出，该机构研究人员在13年内跟踪调查了100多万男性，其中部分人的女性伴侣患有乳腺癌。

研究结果显示，女性伴侣患有乳腺癌的男性患抑郁症等精神类疾病的比例要比常人高出40％，且女性伴侣的病情越严重，男性患抑郁症的风险也越高。如其女性伴侣因乳腺癌而死亡，这部分男性患抑郁症的几率达到正常人的4倍。

丹麦癌症学会教授克里斯托弗·约翰森指出，这项研究提示医护人员在治疗乳腺癌患者的同时，也应关注患者伴侣的精神健康。（生物谷Bioon.com）

生物谷推荐英文摘要：

Cancer DOI: 10.1002/cncr.25534

Increased risk of severe depression in male partners of women with breast cancer?
Naoki Nakaya PhD1,2,3,*,?, Kumi Saito-Nakaya PhD1,2, Pernille Envold Bidstrup PhD1, Susanne Oksbjerg Dalton MD, PhD1, Kirsten Frederiksen PhD4, Marianne Steding-Jessen PhD4, Yosuke Uchitomi MD, PhD2, Christoffer Johansen MD, PhD, DMSc1,5

BACKGROUND:
A few small studies published to date have suggested that major psychosocial problems develop in the partners of cancer patients; however, to the authors' knowledge, no studies to date have addressed their risk for severe depression. In a retrospective cohort study, the risk for hospitalization with an affective disorder of the male partners of women with breast cancer was investigated, using unbiased, nationwide, population-based information.

METHODS:
Followed were 1,162,596 men born between 1925 and 1973 who were aged ≥30 years at study entry, resided in Denmark between 1994 and 2006, had no history of hospitalization for an affective disorder, and had lived continuously with the same partner for at least 5 years. A Cox regression analysis included detailed clinical information regarding the diagnosis and treatment of breast cancer and on annually updated socioeconomic and health-related indicators obtained from national administrative and disease registers.

RESULTS:
During the 13 years of follow-up, breast cancer was diagnosed in the partners of 20,538 men. On multivariable analysis, men whose partner was diagnosed with breast cancer were found to be at an increased risk of being hospitalized with an affective disorder (hazards ratio, 1.39; 95%confidence interval, 1.20-1.61), with a dose-response pattern for the severity of breast cancer. Furthermore, men whose partner died after breast cancer had a significant, 3.6-fold increase in risk for an affective disorder when compared with men whose partner survived breast cancer.

CONCLUSIONS:
The results of the current study supported the hypothesis that men whose partner had breast cancer were at an increased risk for hospitalization with an affective disorder. Cancer 2010. ? 2010 American Cancer Society.